FEATURES OF 3D PRINTING OF ORAL FILMS


Abstract views: 104 / PDF downloads: 30

Authors

  • Bohdan Misan Kharkiv National University of Radio Electronics
  • Igor Nevliudov Kharkiv National University of Radio Electronics
  • Olena Ruban Kharkiv National University of Radio Electronics
  • Abidin Kılıç Eskisehir Technical University

DOI:

https://doi.org/10.5281/zenodo.12705445

Keywords:

3D Printing, clinical integration of new drugs

Abstract

3D printing technology is revolutionizing the medical industry by offering personalized and efficient solutions for the production of medical devices, implants, and prostheses. This technology enables the creation of complex geometric shapes that were previously unachievable or impractical with traditional manufacturing methods, significantly enhancing the personalization of treatment while reducing both cost and production time. The development of new polymer materials is expanding the capabilities of this technology, improving the biocompatibility, mechanical properties, and biodegradability of materials. Techniques such as Stereolithography (SLA), Selective Laser Sintering (SLS), Digital Light Processing (DLP), Fused Deposition Modeling (FDM), and MultiJet Printing (MJP) are increasingly used to produce accurate medical prototypes. Despite the vast opportunities 3D printing technology offers for personalized treatment and medical device production, several critical challenges remain. Material safety is of paramount concern, as not all materials used are adequately tested for biocompatibility and compliance with medical standards. Ensuring high accuracy and quality in 3D printed products also presents significant challenges, particularly when scaling up production. Additionally, regulatory issues concerning the classification and certification of 3D-printed medical devices need more standardized and unified approaches. Another significant issue is the high cost associated with 3D printing technologies and materials, which can restrict their accessibility, especially in developing countries. However, ongoing software development and improvements in technological processes hold the potential to overcome these barriers, significantly expanding the role of 3D printing in healthcare.

References

Díaz-Rodríguez, J. G., et al. (2021). Mechanical properties for long fibre reinforced fused deposition manufactured composites. Composites Part B: Engineering.

Rath, U.; Pandey, P.M. Experimental Investigations into Extrusion-Based 3D Printing of PCL/CIP Composites for Microwave Shielding Applications. J. Thermoplast. Compos. Mater. 2022, 35, 998–1021. [Google Scholar] [CrossRef]

Arrigo, R.; Frache, A. FDM Printability of PLA Based-Materials: The Key Role of the Rheological Behavior. Polymers 2022, 14, 1754. [Google Scholar] [CrossRef] [PubMed]

Kurakula, M.; Koteswara Rao, G.S.N. Moving Polyvinyl Pyrrolidone Electrospun Nanofibers and Bioprinted Scaffolds toward Multidisciplinary Biomedical Applications. Eur. Polym. J. 2020, 136, 109919. [Google Scholar] [CrossRef]

Goyanes, A.; Kobayashi, M.; Martínez-Pacheco, R.; Gaisford, S.; Basit, A.W. Fused-Filament 3D Printing of Drug Products: Microstructure Analysis and Drug Release Characteristics of PVA-Based Caplets. Int. J. Pharm. 2016, 514, 290–295. [Google Scholar] [CrossRef] [PubMed]

Panraksa, P.; Udomsom, S.; Rachtanapun, P.; Chittasupho, C.; Ruksiriwanich, W.; Jantrawut, P. Hydroxypropyl Methylcellulose E15: A Hydrophilic Polymer for Fabrication of Orodispersible Film Using Syringe Extrusion 3D Printer. Polymers 2020, 12, 2666. [Google Scholar] [CrossRef]

Schmidt, L.M.; dos Santos, J.; de Oliveira, T.V.; Funk, N.L.; Petzhold, C.L.; Benvenutti, E.V.; Deon, M.; Beck, R.C.R. Drug-Loaded Mesoporous Silica on Carboxymethyl Cellulose Hydrogel: Development of Innovative 3D Printed Hydrophilic Films. Int. J. Pharm. 2022, 620, 121750. [Google Scholar] [CrossRef]

Moroni, S.; Khorshid, S.; Aluigi, A.; Tiboni, M.; Casettari, L. Poly(3-Hydroxybutyrate): A Potential Biodegradable Excipient for Direct 3D Printing of Pharmaceuticals. Int. J. Pharm. 2022, 623, 121960. [Google Scholar] [CrossRef]

Nevliudov, I., Yevsieiev, V., Maksymova, S., & Chala, O. (2023). A small-sized robot prototype development using 3D printing. In Proceedings of the XXXI International Conference on CAD in Machinery Design Implementation and Educational Issues (p. 12). October 26-28, 2023.

Nevliudov, I., Nikitin, D., Badanyuk, I., Strelets, R., & Korotun, Y. (2023). Factor Analysis of Photopolymer Resins for 3D Printing. Journal of Natural Sciences and Technologies, 1(1), 166-172. https://doi.org/10.5281/zenodo.8088615

Published

2024-07-15

How to Cite

Misan, B., Nevliudov, I., Ruban, O., & Kılıç, A. (2024). FEATURES OF 3D PRINTING OF ORAL FILMS. Journal of Natural Sciences and Technologies, 3(1), 262–265. https://doi.org/10.5281/zenodo.12705445

Most read articles by the same author(s)